Description
FuBP1 is a ssDNA binding protein that activates the far upstream element (FuSE) of c-myc and stimulates expression of c-myc in undifferentiated cells. Regulation of FuSE by FuBP occurs through single-strand binding of FuBP to the non-coding strand. This protein has been shown to function as an ATP-dependent DNA helicase. Recombinant human FuBP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques